On May 14, 2013, the Food and Drug Administration (FDA) approved Tarceva which contain Erlotinib for the first-line treatment of patients with metastatic non-small cell lung cancer.
This drug is used for dealing of patients with metastatic or locally advanced non-small cell lung cancer (NSCLC) who have failed at least one previous round of chemotherapy. It also is used for maintenance of NSCLC that has not progressed after four cycles of platinum-based first line chemotherapy. This drug is combined with gemcitabine to treat advanced unresectable metastatic prostate cancer and for pancreatic cancer.
The usual dose of this drug is 150 mg daily for NSCLC and 100 mg daily for pancreatic cancer. It should be taken on an empty stomach at least one hour before or two hours after eating because food may reduce the absorption of this drug.
Before taking this medicine, tell your doctor or pharmacist if you are allergic to it; or if you have any other reactions. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney problems, stomach/intestinal disease.Use carefulness with sharp objects like safety razors or nail cutters and avoid activities such as contact sports to lower the chance of getting cut, bruised or injured.This medicine may increase your risk of stomach bleeding. Limit alcoholic beverages.Sunlight may worsen any skin reactions that may occur while you are taking this drug. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sun protector cream and wear protective clothing when outdoors.This drug is not suggested for use during pregnancy. It may cause harm to an unborn baby. Women of childbearing age should use reliable form(s) of contraceptive during treatment and for at least 2 weeks following the end of treatment with this drug.Side effects:
Unsettled stomach, vomiting, loss of appetite, mouth sores, dry skin, eye dryness/irritation, or unusual eyelash growth may occur. Changes in diet such as eating several small meals or limiting activity may help lessen the chance of nausea. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.