Physiologic menopause refers to the normal decline in the ovarian function due to ageing which occurs between 45 and 55 years of age. Contrarily, Pathologic or premature menopause refers to the gradual or abrupt cessation of menstruation before the age of 40. According to Professional Guide to Diseases (Eighth Edition), approximately 5% of the women in the US face pathologic menopause. Irrespective of the type of menopause, a woman is bound to experience certain symptoms resulting from the fall in the levels of estrogen hormone. The extent of the symptoms experienced by a woman varies from mild to severe. Activella is a popularly used prescription hormone replacement medication manufactured by Novo Nordisk.
Applications of Activella
Activella (the generic names being estradiol and norethindrone) contains estrogen and progesterone hormones and has been approved by the health authorities for treating various menopause related symptoms. The medicine works by replacing the estrogen that the ovaries no longer produce and keeps the bones strong. The progesterone hormone in the drug decreases the risk of uterus cancer in postmenopausal women.
Some major symptoms of menopause are:Hot flashesIrregular or no periodsMood SwingsIrritabilitySleep disturbancesAnxietyWeight GainBreast tendernessUrinary tract infectionLeakage of the urineVaginal drynessDiscomfort with sexLoss of LibidoApart from these menopausal symptoms and the resultant decrease in hormones, you might also suffer from serious complications, such as osteoporosis, fractures and heart diseases. Of these aforementioned symptoms, Activella can be used for treating or preventing:Itching, burning or dryness in or around vaginaHot flashesOsteoporosisActivella: Recommended Dosage and Side Effects
Since Activella is a prescription medicine, one should always consult a doctor before taking it. The drug comes in two strengths of:1mg/0.5mg- 1mg of estradiol and 0.5mg of noetindrone acetate per tablet0.5mg/0.1mg-0.5mg of estradiol and 0.1mg of norethindrone acetate per tabletThe doctor will decide the recommended dosage for you depending on the severity and the type of menopause symptoms and any other medical conditions you might be suffering from. The generally recommended dosage of this drug is one tablet daily. Although the drug can be safely consumed by most patients, some of common side effects include:Vaginal bleedingBreast painHeadachesUpper respiratory tract infectionsAnd accidental injuriesThose taking this medicine, or any other medicine with a combination of estradiol and norethindrone, should have yearly physical checkups besides examining their breasts for lumps on a monthly basis.
Activella should not be taken if:You have had your uterus removedYou have unusual vaginal bleedingHave or had uterus or breast cancerHave had a stroke or a heart attack in the past one yearHave or had blood clotsHave liver problemsYou are pregnant or breast feeding